Przejdź do zawartości
Merck

HLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

Synonimy:
CD, CELIAC1, DQ-A1, GSE, HLA-DQA
Gatunek:
Human HLA-DQA1 (3117)
Identyfikator UniProtKB:
P01909, O19630, O19706, P01907, P01908, P04225, P04226, P05536
Identyfikator genu:
  • Human(3117) Summary: HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4700650
Monoclonal Anti-HLA-DQ1-DQ3 antibody produced in mouse, clone HL-37, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
HPA012315
Anti-HLA-DQA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
SAB5700946
Anty-HLA-DQA1, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
MABF3078
Anti-HLA‑DQA1 Antibody, clone SPV-L3, ,
Reaktywność gatunkowa
human
Zastosowanie
blocking
flow cytometry
immunoprecipitation (IP)
SAB1402223
Monoclonal Anti-HLA-DQA1 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU111801
MISSION® esiRNA, targeting human HLA-DQA1,
Gatunek
human