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Merck

HLA-DMA

major histocompatibility complex, class II, DM alpha

Synonimy:
D6S222E, DMA, HLADM, RING6
Gatunek:
Human HLA-DMA (3108)
Identyfikator UniProtKB:
P28067, Q29639, Q29640
Identyfikator genu:
  • Human(3108) Summary: HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
WH0003108M1
Monoclonal Anti-HLA-DMA antibody produced in mouse, clone 3F12-F11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
HPA012750
Anti-HLA-DMA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
HPA017295
Anty-HLA-DMA, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence