GALR2
galanin receptor 2
Synonimy:
GAL2-R, GALNR2, GALR-2
Gatunek:
Human GALR2 (8811), Mouse Galr2 (14428), Rat Galr2 (29234), cow GALR2 (618629), domestic cat GALR2 (101096429), naked mole-rat Galr2 (101706932), chicken GALR2 (770030), Horse GALR2 (100051251), dog GALR2 (483325), sheep GALR2 (101118117)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(8811) Summary: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008]
- Mouse(14428) galanin receptor 2
- Rat(29234) galanin receptor 2
- cow(618629) galanin receptor 2
- domestic cat(101096429) galanin receptor 2
- naked mole-rat(101706932) galanin receptor 2
- chicken(770030) galanin receptor 2
- Horse(100051251) galanin receptor 2
- dog(483325) galanin receptor 2
- sheep(101118117) galanin receptor 2
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Antibodies
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Zastosowanie
Anti-GALR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Proteins
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esiRNA
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