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ERVW-1

endogenous retrovirus group W, member 1

Synonimy:
ENV, ENVW, ERVWE1, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV
Gatunek:
Human ERVW-1 (30816)
Identyfikator UniProtKB:
Q9UQF0, B2RPD4, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3
Identyfikator genu:
  • Human(30816) Summary: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB2108834
Anti-ERVW-1 (N-terminal) antibody produced in rabbit biotin conjugated, affinity isolated antibody,
Reaktywność gatunkowa
human, rat
Zastosowanie
SAB2108835
Anti-ERVW-1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Reaktywność gatunkowa
human, rat
Zastosowanie
SAB2108836
Anti-ERVW-1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Reaktywność gatunkowa
human, rat
Zastosowanie
SAB2108833
Anti-ERVW-1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU107361
MISSION® esiRNA, targeting human ERVW-1,
Gatunek
human