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DIABLO

diablo, IAP-binding mitochondrial protein

Synonimy:
DFNA64, SMAC
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Mouse(66593) diablo homolog (Drosophila)
  • Rat(288753) diablo, IAP-binding mitochondrial protein
  • chicken(416860) diablo, IAP-binding mitochondrial protein
  • cow(493999) diablo, IAP-binding mitochondrial protein
  • domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
  • naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
  • sheep(101121971) diablo, IAP-binding mitochondrial protein
  • dog(477463) diablo, IAP-binding mitochondrial protein

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Mouse Diablo / Diablo Homolog, Mitochondrial ELISA Kit, ,
Gatunek
mouse
Rat DIABLO / Diablo Homolog (Drosophila) ELISA Kit, ,
Gatunek
rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SMAC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Smac antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anty-Smac/Diablo, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-Smac/Diablo, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-Smac/DIABLO Antibody, clone 2B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human DIABLO, RP11-512M8.5,
Gatunek
human
MISSION® esiRNA, targeting mouse Diablo,
Gatunek
mouse