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DEFA1

defensin, alpha 1

Synonimy:
DEF1, DEFA2, HNP-1, HP-1, HP1, MRS
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1667) Summary: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, May 2010]
  • Mouse(13216) defensin, alpha 1
  • Horse(100307002) defensin, alpha 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-DEFA1, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, rhesus macaque
Zastosowanie
flow cytometry
western blot
Anty-DEFA1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Proteins

Numer produktu
Opis
Gatunek
Defensin HNP-2 human, ≥95% (HPLC),
Gatunek
human