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Merck

CYP2C8

cytochrome P450, family 2, subfamily C, polypeptide 8

Synonimy:
CPC8, CYPIIC8, MP-12/MP-20
Gatunek:
Human CYP2C8 (1558)
Identyfikator UniProtKB:
P10632, A8K9N8, B0AZN2, B7Z1F6, Q5VX93, Q8WWB1, Q9UCZ9
Identyfikator genu:
  • Human(1558) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4500589
Anti-Cytochrome P450 2C8 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
HPA013547
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
SAB2501735
Anti-CYP2C8 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
HPA013970
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
T9652
Terfenadine, ,
Gatunek
mouse, rat, human

esiRNA

Numer produktu
Opis
Gatunek
EHU068961
MISSION® esiRNA, targeting human CYP2C8,
Gatunek
human