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CLDN8

claudin 8

Synonimy:
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(9073) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]
  • Mouse(54420) claudin 8
  • Rat(304124) claudin 8
  • naked mole-rat(101707430) claudin 8
  • domestic guinea pig(100735357) claudin 8
  • cow(538761) claudin 8
  • sheep(101106811) claudin 8
  • dog(478401) claudin 8
  • domestic cat(101096909) claudin 8
  • Zebrafish(445278) claudin 8
  • chicken(427974) claudin 8

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CLDN8 (196-210) antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-CLDN8 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-CLDN8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CLDN8,
Gatunek
human