CKMT1A
creatine kinase, mitochondrial 1A
Synonimy:
CKMT1
Gatunek:
Human CKMT1A (548596), chicken CKMT1A (374002), Domestic Rabbit CKMT1A (100328683), domestic guinea pig Ckmt1a (100725326)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(548596) Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
- chicken(374002) creatine kinase, mitochondrial 1A
- Domestic Rabbit(100328683) creatine kinase, mitochondrial 1A
- domestic guinea pig(100725326) creatine kinase, mitochondrial 1A
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Antibodies
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Zastosowanie
Anti-CKMT1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
esiRNA
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