1076363

Brinzolamide

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2?6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide, (R)- 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide, AL 4862
• Empirical Formula (Hill Notation): C₁₂H₂₁N₃O₅S₃
• CAS Number: 138890-62-7
• Molecular Weight: 383.51
• NACRES: NA.24
• PubChem Substance ID: 329749130
• UNSPSC Code: 41116107
• MDL number: MFCD08067749

Properties

• grade: pharmaceutical primary standard
• API family: brinzolamide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
• InChI: 1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
• InChI key: HCRKCZRJWPKOAR-JTQLQIEISA-N
• Gene Information: human ... CA2(760)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Brinzolamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Brinzolamide Ophthalmic Suspension

Biochem/physiol Actions

Brinzolamide is a carbonic anhydrase II inhibitor

Brinzolamide is a carbonic anhydrase II inhibitor used to lower intraocular pressure.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable