T5067

Anti-TRPC3 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-Transient receptor potential cation channel, subfamily C, member 3
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD02686005
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 11

Properties

• biological source: rabbit
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: rat
• concentration: ≥0.6 mg/mL (after reconstitution)
• technique(s): western blot: suitable
• UniProt accession no.: Q9JMI9
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Trpc3(22065) ; rat ... Trpc3(60395)

Description

General description

Transient receptor potential-canonical 3 (TRPC3) is a member of TRP superfamily. It is mainly expressed in brain. The TRPC3 gene is mapped to human chromosome 4.

Immunogen

peptide corresponding to amino acid residues 822-835 of mouse TRPC3.

Biochem/physiol Actions

TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo. TRPC3 plays a key role in a wide spectrum of Ca²⁺ signaling mechanisms. Elevated expression of TRPC3 has been observed in spontaneously hypertensive rats (SHR).

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)