Skip to Content
Merck
All Photos(2)

Documents

T3766

Sigma-Aldrich

Thymine 1-β-D-arabinofuranoside

≥99%

Synonym(s):

araT, 1-β-D-Arabinofuranosylthymine

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C10H14N2O6
CAS Number:
605-23-2
Molecular Weight:
258.23
EC Number:
210-083-7
MDL number:
MFCD00065474
UNSPSC Code:
41106305
PubChem Substance ID:
24900167
NACRES:
NA.51

Assay

≥99%

form

powder

optical activity

[α]20/D 90°, c = 5 mg/mL in water

solubility

0.5 M HCl: 20 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

CC1=CN(C2OC(CO)C(O)C2O)C(=O)NC1=O

InChI

1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)

InChI key

DWRXFEITVBNRMK-UHFFFAOYSA-N

Application

1-β-D-Arabinofuranosylthymine (araT):
  • maybe used as a substrate and inhibitor to study the specificity and kinetics of thymidine kinase(s), such as herpes simplex virus type 1 and 2 thymidine kinases, the HSV1-tk and, HSV2-tk gene products.
  • is used to study the specificity and kinetics of various mitochondrial nucleoside kinases.
  • has been used as an antiviral agent to study its efficacy on Cryptosporidium parvum in vitro.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xiuyun Wang et al.
Nature communications, 11(1), 653-653 (2020-02-02)
The industrial synthesis of ammonia (NH3) using iron-based Haber-Bosch catalyst requires harsh reaction conditions. Developing advanced catalysts that perform well at mild conditions (<400 °C, <2 MPa) for industrial application is a long-term goal. Here we report a Co-N-C catalyst with high
Kristof Y Neven et al.
Scientific reports, 10(1), 161-161 (2020-01-15)
Iodine is an essential trace element, necessary for the production of thyroid hormones, which play a key role in optimal foetal growth and (neuro-) development. To date, iodine deficiency remains a health burden in many countries. We investigated the variability
Efficacy of select antivirals against Cryptosporidium parvum in vitro
Woods KM and Upton SJ
FEMS Microbiology Letters, 168(1), 59-63 (1998)
Alex McAvoy et al.
PLoS computational biology, 11(8), e1004349-e1004349 (2015-08-27)
Evolutionary game theory is a powerful framework for studying evolution in populations of interacting individuals. A common assumption in evolutionary game theory is that interactions are symmetric, which means that the players are distinguished by only their strategies. In nature
Xinyu Zheng et al.
Cancer research, 63(20), 6909-6913 (2003-10-30)
Nucleoside kinases from several species are investigated as suicide genes for treatment of malignant tumors by combined gene/chemotherapy. In the present study, we have investigated a novel strategy where nucleoside kinase proteins are directly delivered to cells without delivery of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service