SML4007
TMC207
≥98% (HPLC)
Synonym(s):
(αS,βR)-6-Bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol, (1R, 2S)-1-(6-Bromo-2methoxy-3-quinolinyl)-4-(dimethylamino)-2-(1-naphthalenyl)-1-phenyl-2-butanol, Bedaquiline, R 207910, R-207910, R207910
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Please contact Customer Service for Availability | 368,00 PLN |
50 mg | Please contact Customer Service for Availability | 1.480,00 PLN |
About This Item
368,00 PLN
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D 195.0 to 155.0° (c = 0.5g/100mL in DMF)
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
BrC(C=C1)=CC2=C1N=C(OC)C([C@@H](C3=CC=CC=C3)[C@](O)(C4=CC=CC5=C4C=CC=C5)CCN(C)C)=C2
InChI key
QUIJNHUBAXPXFS-XLJNKUFUSA-N
Biochem/physiol Actions
TMC207 (Bedaquiline; R207910) is an orally active, potent and selective mycobacterial ATP synthase inhibitor (M. smegmatis IC50 = 2.5 nM or 1.4 ng (non-salt form)/mL; human mitochondrial ATP syntase IC50 >200 uM) with broad-spectrum anti-mycobacterial activity (MIC 10-120 ng/mL), including M. bovis, avium complex (MAC), kansasii, marinum, fortuitum, abscessus, smegmatis, ulcerans, and both drug-susceptible and multiple drug-resistant M. tuberculosis strains (to rigampin, isoniazid, streptomycin, ethambutol, pyrazinamide, fluoroquinolone).
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC), powder, mycobacterial ATP synthase inhibitor | description NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA. | description NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA. |
| form powder | form powder | form - | form - |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level - |
| storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. - | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility - | solubility - |
| color white to beige | color white to beige | color - | color - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Aquatic Chronic 1
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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