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SML3822

SA-15-P

≥98% (HPLC)

Synonym(s):

N-[4-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethoxy]phenyl]-2-furancarboxamide

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
777,00 PLN
25 mg
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2.270,00 PLN

About This Item

Empirical Formula (Hill Notation):
C26H24N2O4
CAS Number:
Molecular Weight:
428.48
NACRES:
NA.21
UNSPSC Code:
51111800
Assay:
≥98% (HPLC)
Form:
powder

777,00 PLN


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

LAG-3 (CD223) inhibitor that blocks LAG-3 interactions with both major histocompatibility complex class II (MHCII) and fibrinogen-like protein 1 (FGL1).
SA-15-P is a LAG-3 (CD223) inhibitor that blocks LAG-3 interactions with both major histocompatibility complex class II and fibrinogen-like protein 1 by cell-free (MHCII IC50 = 4.21 μM & FGL1 IC50 = 6.52 μM) and cell-based binding assays (IC50 ~15 μM against 150 ng/mL or 1.5 nM FGL1-hFc binding to stable LAG-3-expressing CHO-K1 cell line).


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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