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SML3753

TH301

≥98% (HPLC)

Synonym(s):

1-​(4-​Chlorophenyl)​-​N-​[2,​6-​dihydro-​2-​(4-​methoxyphenyl)​-​5,​5-​dioxido-​4H-​thieno[3,​4-​c]​pyrazol-​3-​yl]​-cyclopentanecarboxam​ide

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
777,00 PLN
25 mg
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3.140,00 PLN

About This Item

Empirical Formula (Hill Notation):
C24H24ClN3O4S
CAS Number:
Molecular Weight:
485.98
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder

777,00 PLN


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1(CCCC1)C2=CC=C(Cl)C=C2)NC3=C(CS(C4)(=O)=O)C4=NN3C5=CC=C(OC)C=C5

InChI

1S/C24H24ClN3O4S/c1-32-19-10-8-18(9-11-19)28-22(20-14-33(30,31)15-21(20)27-28)26-23(29)24(12-2-3-13-24)16-4-6-17(25)7-5-16/h4-11H,2-3,12-15H2,1H3,(H,26,29)

InChI key

DDCUCVXSGYHWRJ-UHFFFAOYSA-N

Biochem/physiol Actions

Circadian clock modulator that selectively stabilizes CRY2
TH301 is a circadian clock modulator that lengthens a circadian period in cells and tissues. It selectively stabilizes CRY2 through interaction with FAD-binding pocket. TH301 strongly enhanced brown adipocyte differentiation in culture. TH301 showed no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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