Skip to Content
Merck
All Photos(1)

Documents

SML3717

Sigma-Aldrich

C11-BODIPY581/591

≥95% (HPLC)

Synonym(s):

(T-4)-Difluoro[5-[[5-[(1E,3E)-4-phenyl-1,3-butadien-1-yl]-2H-pyrrol-2-ylidene-κN]methyl]-1H-pyrrole-2-undecanoato(2-)-κN1]-borate(1-), monohydrogen, BODIPY 581/591 C11, BP-C11, Borate(1-), (T-4)-difluoro[5-[[5-[(1E,3E)-4-phenyl-1,3-butadien-1-yl]-2H-pyrrol-2-ylidene-κN]methyl]-1H-pyrrole-2-undecanoato(2-)-κN1]-, hydrogen (1:1), C11 BODIPY(581/591), C11 BODIPY581/591, C11-BDP, C11-BODIPY, C11-BP

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C30H35BF2N2O2
CAS Number:
217075-36-0
Molecular Weight:
504.42
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

100

Assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

brown to black

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

C11-BODIPY581/591 is an oxidation-sensitive fluorophore whose maximal ex/em wavelengths shift from 581/591 nm (red) to 500/510 (green) upon lipid peroxidation (LPO). The probe incorporates readily into lipid membranes and is useful for detecting and quantifying LPO of cell-free lipid preparations as well as in live cells by fluorometer (fluorimeter), fluorescence confocal microscopy (dual ex at 488 & 568 nm, detection by 530/30 nm and 590/30 nm bandpass filters) and flow cytometry (ex/em 484/510 for green, ex/em 581/610 for red signal).

Caution

Hygroscopic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice
Scientific Reports, 11(1), 12890-12890 (2021)
Ratio-fluorescence microscopy of lipid oxidation in living cells using C11-BODIPY(581/591)
Febs Letters, 453(3), 278-282 (1999)
Delin Chen et al.
Nature communications, 12(1), 3644-3644 (2021-06-17)
Here, we identify iPLA2β as a critical regulator for p53-driven ferroptosis upon reactive oxygen species (ROS)-induced stress. The calcium-independent phospholipase iPLA2β is known to cleave acyl tails from the glycerol backbone of lipids and release oxidized fatty acids from phospholipids.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service