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SML3553

STF-1084

≥98% (HPLC), ENPP1 inhibitor, powder

Synonym(s):

ENPP1 inhibitor Compound 15, P-​[2-​[1-​(6,​7-​dimethoxy-​4-​quinazolinyl)​-​4-​piperidinyl]​ethyl]​-phosphonic acid

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
345,00 PLN
25 mg
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1.380,00 PLN

About This Item

Empirical Formula (Hill Notation):
C17H24N3O5P
CAS Number:
Molecular Weight:
381.36
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

345,00 PLN


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Product Name

STF-1084, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=P(O)(O)CCC(CC1)CCN1C2=NC=NC3=C2C=C(OC)C(OC)=C3

InChI

1S/C17H24N3O5P/c1-24-15-9-13-14(10-16(15)25-2)18-11-19-17(13)20-6-3-12(4-7-20)5-8-26(21,22)23/h9-12H,3-8H2,1-2H3,(H2,21,22,23)

InChI key

SNLWMWQNJTVWKD-UHFFFAOYSA-N

Biochem/physiol Actions

Cell-impermeable, potent, selective, stable and nontoxic competitive inhibitor of ENPP1 that inhibit degradation of extracellular cGAMP under physiological conditions
STF-1084 (ENPP1 inhibitor Compound 15) Is a cell-impermeable, potent, selective, stable and nontoxic competitive inhibitor of ENPP1 (ectonucleotide pyrophosphatase phosphodiesterase 1) that inhibit degradation of extracellular cGAMP under physiological conditions. STF-1084 had no effect on intracellular cGAMP. STF-1084 synergized with IR to significantly delay tumor progression in three triple-negative breast cancer cell lines 4T1-luc mice model.

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This Item
SML3582SML3583SML3450
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥95% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

-10 to -25°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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