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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 275,00 PLN |
25 mg | Please contact Customer Service for Availability | 1.110,00 PLN |
About This Item
Empirical Formula (Hill Notation):
C20H22N2O
CAS Number:
Molecular Weight:
306.40
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Quality Segment
assay
≥95% (HPLC)
form
powder
optical activity
[α]/D 295 to 245°
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
-10 to -25°C
InChI key
VTLYEMHGPMGUOT-MKWZCHDOSA-N
Biochem/physiol Actions
Koumine is a major indole alkaloid isolated from poisonous plant Gelsemium elegans that exhibits anti-inflammatory and analgesic effects in inflammatory and neuropathic pain models. It appears that koumine ameliorate chronic constriction injury induced neurotic pain through induction of autophagy and the inhibition apoptosis in the spinal cord of rodents. Koumine protects IPEC-J2 cells from hydrogen peroxide induced oxidative stress and apoptosis through decreasing reactive oxygen species (ROS) production.
Major indole alkaloid isolated from poisonous plant Gelsemium elegans that exhibits anti-inflammatory and analgesic effects
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This Item | |||
|---|---|---|---|
| description ≥95% (HPLC) | description phyproof® Reference Substance | description ≥98% (HPLC) | description ≥95% (HPLC) |
| form powder | form solid | form powder | form powder |
| assay ≥95% (HPLC) | assay ≥90.0% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. -10 to -25°C | storage temp. 2-8°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C |
| solubility DMSO: 2 mg/mL, clear (Warmed) | solubility - | solubility DMSO: 2 mg/mL, clear (Warmed) | solubility DMSO: 2 mg/mL, clear (Warmed) |
| color white to beige | color - | color white to beige | color white to beige |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
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