SML3359

TP-040

≥98% (HPLC)

• Synonym(s): N-((1-Methyl-1H-imidazol-4-yl)methyl)-4-(4-methylpiperidin-1-yl)pyrimidin-2-amine
• Empirical Formula (Hill Notation): C₁₅H₂₂N₆
• CAS Number: 2757254-99-0
• Molecular Weight: 286.38
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC(CC1)CCN1C2=CC=NC(NCC3=CN(C)C=N3)=N2
• InChI: 1S/C15H22N6/c1-12-4-7-21(8-5-12)14-3-6-16-15(19-14)17-9-13-10-20(2)11-18-13/h3,6,10-12H,4-5,7-9H2,1-2H3,(H,16,17,19)
• InChI key: PWKAYICUBVNJAZ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA).

TP-040 is a brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA). TP-040 increases the level of O-GlcNAcylated protein in cells.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable