SML3345

LSL 60101

≥98% (HPLC)

• Synonym(s): 2-(1-Benzofuran-2-yl)-1H -imidazole, 2-(2-Benzofuranyl)-1H -imidazole (ACI), Garsevil, LSL60101
• Empirical Formula (Hill Notation): C₁₁H₈N₂O
• CAS Number: 150985-54-9
• Molecular Weight: 184.19
• UNSPSC Code: 51111800
• NACRES: NA.77
• MDL number: MFCD17292409
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [nH]1c(ncc1)c2[o]c3c(c2)cccc3
• InChI: 1S/C11H8N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-7H,(H,12,13)
• InChI key: VBFQIUOSXHUWCT-UHFFFAOYSA-N

Description

Biochem/physiol Actions

LSL 60101 is an orally available, potent and selective I2 imidazoline receptor ligand that induces morphological/biochemical changes in astroglia and exhibits neuroprotective activity. LSL 60101 decreases neuroinflammation and reverses cognitive deficits and impaired social behavior in 5XFAD mice Alzheimer’s model.

Orally available, potent and selective I2 imidazoline receptor ligand that exhibits neuroprotective activity

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable