SML2932

Dexamethasone palmitate

≥98% (HPLC), corticosteroid prodrug, powder

• Synonym(s): (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione, Dexamethasone 21-palmitate
• Empirical Formula (Hill Notation): C₃₈H₅₉FO₆
• CAS Number: 14899-36-6
• Molecular Weight: 630.87
• NACRES: NA.77
• UNSPSC Code: 51111800
• MDL number: MFCD01698988
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Product Name: Dexamethasone palmitate, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@@]([C@](C(COC(CCCCCCCCCCCCCCC)=O)=O)(O)[C@H](C)C4)(C)[C@]4([H])[C@]3([H])CCC2=C1
• InChI: 1S/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1
• InChI key: WDPYZTKOEFDTCU-WDJQFAPHSA-N

Description

Biochem/physiol Actions

Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.

lipophilic prodrug of a potent corticosteroid dexamethasone

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable