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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 409,00 PLN 347,65 PLN |
25 mg | Please contact Customer Service for Availability | 1.370,00 PLN 1.164,50 PLN |
About This Item
Empirical Formula (Hill Notation):
C14H14ClNO2S
CAS Number:
Molecular Weight:
295.78
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
347,65 PLN
List Price409,00 PLNSave 15%Please contact Customer Service for Availability
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
ClC1=CC=C(OCCNC(C2=CC=CS2)=O)C(C)=C1
InChI
1S/C14H14ClNO2S/c1-10-9-11(15)4-5-12(10)18-7-6-16-14(17)13-3-2-8-19-13/h2-5,8-9H,6-7H2,1H3,(H,16,17)
InChI key
RULQUKFOBAPKKR-UHFFFAOYSA-N
Biochem/physiol Actions
Activator of K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels
ML402 is a selective activator of K2P2.1 (TREK-1) and K2P10.1 (TREK-2) potassium channels. It was used to determine a cryptic selectivity filter binding site of the K2P2.1 (TREK-1) channel, designated the K2P modulator pocket. This binding pocket stabilizes an active "leak-mode" conformation, binding small-molecule activators that restrict the mobility of the selectivity filter and surrounding structure.
1 of 1
This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description purified immunoglobulin, buffered aqueous solution | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
| form powder | form buffered aqueous solution | form buffered aqueous glycerol solution |
| assay ≥98% (HPLC) | assay - | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - |
| color white to beige | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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