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SML2146

SR-18292 Maleate

≥98% (HPLC), hepatic gluconeogenesis inhibitor, powder

Synonym(s):

SR-18292 Maleate, 1-[(1,1-Dimethylethyl)[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)-2-propanol maleate, SR 18292, SR 18292 maleate

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
800,00 PLN
680,00 PLN
25 mg
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2.000,00 PLN
1.700,00 PLN

About This Item

Empirical Formula (Hill Notation):
C23H30N2O2 · C4H4O4
CAS Number:
Molecular Weight:
482.57
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

680,00 PLN

List Price800,00 PLNSave 15%

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Product Name

SR-18292 Maleate, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(C)(C)N(CC(O)COC1=CC=CC2=C1C=CN2)CC3=CC=C(C)C=C3.O=C(O)/C=C\C(O)=O

InChI key

CMTOYDGVFTZNSM-BTJKTKAUSA-N

Application

SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor γ coactivator 1 α (PGC1α) inhibitor to study the protective effects of pioglitazone on demyelinated axons.

Biochem/physiol Actions

SR-18292 is a potent and specific inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α and suppression of gluconeogenic gene expression. SR-18292 reduces blood glucose and increases hepatic insulin sensitivity in mouse models of T2D.
inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α; anti-diabetic

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EMU064011
description

≥98% (HPLC)

description

targeting mouse Sebox

form

powder

form

lyophilized powder

assay

≥98% (HPLC)

assay

-

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

-

color

white to beige

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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