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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 590,00 PLN |
25 mg | Please contact Customer Service for Availability | 1.900,00 PLN |
About This Item
Empirical Formula (Hill Notation):
C14H14FNO3
CAS Number:
Molecular Weight:
263.26
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
light orange to dark orange
solubility
DMSO: 25 mg/mL, clear
storage temp.
2-8°C
SMILES string
CC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O
InChI
1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
InChI key
RCVZUIGCNAAMIC-UXBLZVDNSA-N
Biochem/physiol Actions
ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.
ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1).
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC), solid | description targeting mouse Trpa1 | description from rabbit, purified by affinity chromatography |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - | assay - |
| form powder | form solid | form lyophilized powder | form - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| solubility DMSO: 25 mg/mL, clear | solubility DMSO: >10 mg/mL | solubility - | solubility - |
| color light orange to dark orange | color white to off-white | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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