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SML1386

Calindol hydrochloride

≥98% (HPLC)

Synonym(s):

(R)-2-[[[1-(1-Naphthyl)ethyl]amino]methyl]-1H-indole hydrochloride, N-[(1R)-1-(1-naphthalenyl)ethyl]-1H-Indole-2-methanamine hydrochloride

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Size/SKUAvailabilityPrice
5 mg
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1.010,00 PLN

About This Item

Empirical Formula (Hill Notation):
C21H20N2 · HCl
CAS Number:
Molecular Weight:
336.86
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

1.010,00 PLN


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

−20°C

SMILES string

[H]Cl.C[C@@H](NCC1=CC2=C(N1)C=CC=C2)C3=CC=CC4=C3C=CC=C4

InChI

1S/C21H20N2.ClH/c1-15(19-11-6-9-16-7-2-4-10-20(16)19)22-14-18-13-17-8-3-5-12-21(17)23-18;/h2-13,15,22-23H,14H2,1H3;1H/t15-;/m1./s1

InChI key

KFILKQPBQZIRST-XFULWGLBSA-N

Biochem/physiol Actions

Calcimimetic; Ca Sensing Receptor (CaSR) Agonist
Calindol is a calcimimetic Ca Sensing Receptor (CaSR) agonist. It is a positive allosteric modulator (PAM) with an EC50 value of 1 μM and a maximum stimulation of 130% of the 10mM Ca2+ activation in triggering PI hydrolysis.

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This Item
I2909SML0190S1697
description

≥98% (HPLC)

description

≥98% (HPLC), solid

description

≥95% (HPLC)

description

≥98% (HPLC), solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

powder

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 10 mg/mL, clear

solubility

H2O: insoluble, DMSO: ~24 mg/mL

solubility

DMSO: ≥10 mg/mL

solubility

H2O: >5 mg/mL

color

white to beige

color

white to off-white

color

white to tan

color

white


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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