SML0906

HPOB

≥98% (HPLC)

• Synonym(s): 4-[(Hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide
• Empirical Formula (Hill Notation): C₁₇H₁₈N₂O₄
• CAS Number: 1429651-50-2
• Molecular Weight: 314.34
• UNSPSC Code: 12352202
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 1 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: N(O)C(=O)c1ccc(cc1)CC(=O)N(CCO)c2ccccc2
• InChI: 1S/C17H18N2O4/c20-11-10-19(15-4-2-1-3-5-15)16(21)12-13-6-8-14(9-7-13)17(22)18-23/h1-9,20,23H,10-12H2,(H,18,22)
• InChI key: RFAZNTABYJYOAR-UHFFFAOYSA-N

Description

Biochem/physiol Actions

HPOB is a very potent, selective inhibitor of HDAC6.

HPOB is a very potent, selective inhibitor of HDAC6. HPOB inhibits proliferation of normal and transformed cell lines but does not induce cell death. The compound HPOB potentiates the effects of DNA-damaging cytotoxic anti-cancer drugs.

Features and Benefits

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Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable