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SML0127

Longdaysin

≥98% (HPLC)

Synonym(s):

9-isopropyl-N-(3-(trifluoromethyl)benzyl)-9H-purin-6-amine

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
653,00 PLN
555,05 PLN
25 mg
Please contact Customer Service for Availability
1.790,00 PLN

About This Item

Empirical Formula (Hill Notation):
C16H16F3N5
CAS Number:
1353867-91-0
Molecular Weight:
335.33
NACRES:
NA.77
PubChem Substance ID:
329825177
UNSPSC Code:
12352200
MDL number:
MFCD20527323
Assay:
≥98% (HPLC)
Form:
powder

555,05 PLN

List Price653,00 PLNSave 15%
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: ≥15 mg/mL

storage temp.

2-8°C

SMILES string

CC(C)N(C=N1)C2=C1C(NCC3=CC(C(F)(F)F)=CC=C3)=NC=N2

InChI

1S/C16H16F3N5/c1-10(2)24-9-23-13-14(21-8-22-15(13)24)20-7-11-4-3-5-12(6-11)16(17,18)19/h3-6,8-10H,7H2,1-2H3,(H,20,21,22)

InChI key

REKSFCCYDQMSIN-UHFFFAOYSA-N

Application

Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior.

Biochem/physiol Actions

Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.

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This Item
HPA019530EMU065841PHL83756
Longdaysin ≥98% (HPLC)

Sigma-Aldrich

SML0127

Longdaysin

Anti-PER3 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Sigma-Aldrich

HPA019530

Anti-PER3 antibody produced in rabbit

MISSION® esiRNA targeting mouse Per3

Sigma-Aldrich

EMU065841

MISSION® esiRNA

Qingdainone phyproof® Reference Substance

PHL83756

Qingdainone

description

≥98% (HPLC)

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

description

targeting mouse Per3

description

phyproof® Reference Substance

form

powder

form

buffered aqueous glycerol solution

form

lyophilized powder

form

-

assay

≥98% (HPLC)

assay

-

assay

-

assay

≥90.0% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: ≥15 mg/mL

solubility

-

solubility

-

solubility

-

color

white to tan

color

-

color

-

color

-

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Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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