Solute carrier family 14 member 2 (SLC14A2) is composed of 929 amino acids and is expressed in the collecting duct of the inner medulla in rat kidneys. The gene ID of the protein is 54302.
Specificity
Detects ~97 and 127 kDa.
Immunogen
AA911-929 of the rat sequence
Biochem/physiol Actions
Solute carrier family 14 member 2 (SLC14A2) plays a crucial role in increasing the permeability of urea in the collecting ducts of the inner medulla in kidneys of rats. It also helps to maintain the concentration of urine.
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Physical form
PBS, 50% glycerol, and 0.09% sodium azide
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American journal of physiology. Cell physiology, 298(6), C1431-C1437 (2010-05-12)
Of the three major protein variants produced by the UT-A gene (UT-A1, UT-A2, and UT-A3) UT-A1 is the largest. It contains UT-A3 as its NH(2)-terminal half and UT-A2 as its COOH-terminal half. When being part of UT-A1, UT-A3 and UT-A2
Acute liver failure is divided into hyperacute, acute and subacute liver failure. Ascites is a common complication of subacute liver failure. Although animal models of acute liver failure have been established, the study of the pathogenesis of subacute liver failure
American journal of physiology. Renal physiology, 303(2), F201-F208 (2012-04-27)
Urea transporters UT-A1 and UT-A3 are both expressed in the kidney inner medulla. However, the function of UT-A3 remains unclear. Here, we found that UT-A3, which comprises only the NH(2)-terminal half of UT-A1, has a higher urea transport activity than
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