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S8071

Salvinorin A

≥98% (HPLC), solid

Synonym(s):

(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester

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Pack SizeSKUAvailabilityPrice
1 mg
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PLN 920.00
PLN 782.00

About This Item

Empirical Formula (Hill Notation):
C23H28O8
CAS Number:
83729-01-5
Molecular Weight:
432.46
NACRES:
NA.77
PubChem Substance ID:
24899776
UNSPSC Code:
12352200
MDL number:
MFCD05664742
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
protect from light

PLN 782.00

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Quality Level

100

assay

≥98% (HPLC)

form

solid

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

storage condition

protect from light

color

white

solubility

DMSO: ≥10 mg/mL, ethanol: ~3 mg/mL

storage temp.

−20°C

SMILES string

[H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OC(C)=O)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c4ccoc4)C(=O)OC

InChI

1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1

InChI key

OBSYBRPAKCASQB-AGQYDFLVSA-N

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)
rat ... Oprk1(29335)

Application

Salvinorin A was administered to rats to study effects on lactic acid-stimulated stretching.1

Biochem/physiol Actions

Salvanorin A is a non-nitrogenous κ opioid receptor agonist.
Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
75250SML0545F131
Salvinorin A ≥98% (HPLC), solid

Sigma-Aldrich

S8071

Salvinorin A

Salvinorin B ≥93.0% (HPLC)

Sigma-Aldrich

75250

Salvinorin B

CID 1067700 ≥98% (HPLC)

Sigma-Aldrich

SML0545

CID 1067700

FPL 64176 ≥98% (HPLC), powder

Sigma-Aldrich

F131

FPL 64176

assay

≥98% (HPLC)

assay

≥93.0% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

solid

form

powder or crystals

form

powder

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

drug control

-

drug control

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥10 mg/mL, ethanol: ~3 mg/mL

solubility

chloroform: soluble

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: >20 mg/mL (Solutions should be freshly prepared.), H2O: insoluble

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW9510
MKCT3685
MKCP8805
MKCM8644
MKCL7574

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Francesca Guida et al.
Molecular pain, 8, 60-60 (2012-08-24)
Salvinorin A (SA), the main active component of Salvia Divinorum, is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to reduce acute pain and to exert potent antinflammatory effects. This study assesses the effects and the mode
Justyna Piekielna et al.
Postepy biochemii, 58(4), 485-491 (2012-01-01)
Salvinorin A (SA) is the main active ingredient of Salvia divinorum, a naturally occurring hallucinogen plant from Mexico. Traditionally, herbal preparations obtained from Salvia were used by the Mazatec Indians for their divination rites and the treatment of gastrointestinal disorders.
John Stogner et al.
The International journal on drug policy, 23(6), 512-521 (2012-04-17)
A plant with dissociative and psychoactive properties began to attract the attention of the media and United States policymakers following a well-publicized suicide in 2006 and reports that the plant served as a 'legal high' and substitute for cannabis. As
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Global Trade Item Number

SKUGTIN
S8071-1MG04061826203637

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