S009
LY-165,163
solid
Synonym(s):
4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzeneamine, p-Aminophenethyl-m-trifluoromethylphenyl piperazine, PAPP
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About This Item
Empirical Formula (Hill Notation):
C19H22F3N3
CAS Number:
Molecular Weight:
349.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Form:
solid
form
solid
color
off-white
solubility
0.1 M HCl: slightly soluble, H2O: insoluble, ethanol: freely soluble
SMILES string
Nc1ccc(CCN2CCN(CC2)c3cccc(c3)C(F)(F)F)cc1
InChI
1S/C19H22F3N3/c20-19(21,22)16-2-1-3-18(14-16)25-12-10-24(11-13-25)9-8-15-4-6-17(23)7-5-15/h1-7,14H,8-13,23H2
InChI key
GAAKALASJNGQKD-UHFFFAOYSA-N
Gene Information
human ... HTR1A(3350), HTR1D(3352)
Biochem/physiol Actions
Selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Alireza Nasoori
Biological reviews of the Cambridge Philosophical Society, 95(4), 986-1019 (2020-04-28)
This review describes the formation, structure, and function of bony compartments in antlers, horns, ossicones, osteoderm and the os penis/os clitoris (collectively referred to herein as AHOOO structures) in extant mammals. AHOOOs are extra-skeletal bones that originate from subcutaneous (dermal)
J S Sprouse et al.
Neuropharmacology, 27(7), 707-715 (1988-07-01)
In low cerveau isolé transected rats, the effects of microiontophoretic application of putative serotonin 5-HT1A and 5-HT1B agonists on the spontaneous firing rate of CA1 pyramidal cells were compared to those of 5-HT. In contrast to the large current-dependent suppression
M De Vivo et al.
Biochemical pharmacology, 40(7), 1551-1558 (1990-10-01)
5-Hydroxytryptamine (serotonin, 5-HT) stimulates basal adenylyl cyclase activity in membranes from guinea pig or rat hippocampi, but 5-HT inhibits forskolin-stimulated adenylyl cyclase activity in these same membranes. The opposing effects of 5-HT on adenylyl cyclase activity indicate that distinct 5-HT
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S009-25MG | 04061832093246 |