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RAB1475

Sigma-Aldrich

Human Galectin-9 ELISA

for serum, plasma and cell culture supernatants

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 36 pg/mL
standard curve range: 36.86-9000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LGALS9(3965)

General description

Galectin-9 is generally a part of extracellular secretions but is also localized to endothelial cells, T cells and dendritic cells. Galectin-9 is a S-type lectin and its gene is mapped to human chromosome 17q11.2.
This ELISA antibody pair detects Human Galectin-9 (LGALS9)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Galectin is a β-galactoside-binding secretory protein, which also has a carbohydrate-recognition domain. Galectin contributes to cancer progression by interacting with oncogenic proteins on the cell surface, such as integrins, fibronectin and laminin. Galectin is also known to suppress immune response in conditions such as melanoma, neuroblastoma and pancreatic carcinoma.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elevated Galectin-9 Suppresses Th1 Effector Function and Induces Apoptosis of Activated CD4+ T Cells in Osteoarthritis.
Yang S, et al.
Inflammation, 40(3), 1062-1071 (2017)
Characterization of a de novo sSMC 17 detected in a girl with developmental delay and dysmorphic features.
Stavber L, et al.
Molecular Cytogenetics, 10(1), 10-10 (2017)
Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-kB signaling pathway.
Luo L H, et al.
Biochemical and Biophysical Research Communications, 491(4), 966-972 (2017)
Galectin-9 binds to O-glycans on protein disulfide isomerase.
Schaefer K, et al.
Glycobiology, 27(9), 878-887 (2017)
Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells.
KeeSoo N, et al.
Oncotarget, 8(22), 35804-35823 (2017)
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