P9768
Phorbol 12,13,20-triacetate
powder
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About This Item
Empirical Formula (Hill Notation):
C26H34O9
CAS Number:
Molecular Weight:
490.54
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
form
powder
color
white
storage temp.
−20°C
SMILES string
CC1C(OC(C)=O)C2(OC(C)=O)C(C3C=C(COC(C)=O)CC4(O)C(C=C(C)C4=O)C13O)C2(C)C
InChI
1S/C26H34O9/c1-12-8-19-24(31,21(12)30)10-17(11-33-14(3)27)9-18-20-23(6,7)26(20,35-16(5)29)22(34-15(4)28)13(2)25(18,19)32/h8-9,13,18-20,22,31-32H,10-11H2,1-7H3/t13-,18+,19-,20-,22-,24-,25-,26-/m1/s1
InChI key
LASMKIAVFGUYEG-SEYWVDNQSA-N
signalword
Danger
Hazard Classifications
Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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C K Too et al.
Endocrinology, 121(4), 1503-1511 (1987-10-01)
Stimulation of mitogenesis in rat Nb2 node lymphoma cells by human (h) PRL was inhibited by inhibitors of Na+/H+ exchange (viz. amiloride and its analogs) and inhibitors of protein kinases (isoquinolinesulfonamide derivatives). The most potent were ethylisopropylamiloride (EP-Am) (IC50, 13
Gary Glenn et al.
FEBS letters, 581(28), 5377-5381 (2007-10-31)
The CSF-1 receptor is a protein-tyrosine kinase that has been shown to undergo regulated intramembrane proteolysis, or RIPping. Here, we have compared receptor downregulation and RIPping in response to CSF-1 and TPA. Our studies show that CSF-1 is a relatively
K R Stratton et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(7), 2498-2501 (1989-04-01)
We have used the hippocampal slice preparation to investigate the regulation of protein tyrosine phosphorylation in brain. After pharmacological treatment of intact slices, proteins were separated by electrophoresis, and levels of protein tyrosine phosphorylation were assessed by immunoblotting with specific
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P9768-5MG | 04061832865362 |