The long-term stability of a stock solution stored at -20ºC has not been evaluated. It is recommended to prepare stock solutions in degassed water and store them in working aliquots in order to extend the stability. Solutions stored refrigerated are stable for 30 days. Frozen aliquots would be expected to be stable for at least as long as the refrigerated solution.
P5780
Putrescine dihydrochloride
powder, BioReagent, suitable for cell culture
Synonym(s):
1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride
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| Size/SKU | Availability | Price |
|---|---|---|
5 g | Please contact Customer Service for Availability | PLN 330.00 |
25 g | Please contact Customer Service for Availability | PLN 575.00 |
About This Item
Linear Formula:
NH2(CH2)4NH2 · 2HCl
CAS Number:
Molecular Weight:
161.07
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
206-375-9
Beilstein/REAXYS Number:
3906680
MDL number:
Assay:
≥97% (TLC)
Form:
powder
Quality Segment
biological source
microbial, synthetic
product line
BioReagent
assay
≥97% (TLC)
form
powder
technique(s)
cell culture | mammalian: suitable
mp
280 °C (dec.) (lit.)
solubility
H2O: 100 mg/mL
SMILES string
Cl[H].Cl[H].NCCCCN
InChI
1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H
InChI key
XXWCODXIQWIHQN-UHFFFAOYSA-N
General description
Putrescine is an end product of fatty acid metabolism in dead tissues. It is a volatile diamine with pungent odour. It is synthesized by the decarboxylation of ornithine in the presence of enzyme, ornithine decarboxylase. Molecular docking studies reveal the binding of putrescine to human receptors called the trace amine-associated receptors (TAAR6 and TAAR8), present in olfactory epithelium.
Application
Putrescine dihydrochloride has been used as medium component in F-12 + GlutaMax medium for mice ganglia culture, retinal ganglion cell culture[1] and in HCT116 colon carcinoma cells for ornithine decarboxylase (ODC) assay.
Biochem/physiol Actions
Putrescine is regarded as a marker of stress in plants. External supplementation of putrescine helps wheat plants to overcome drought stress. It is crucial for cell proliferation in animals and modulates abscisic acid (ABA) levels during cold stress in Arabidopsis plants. It serves as an attractant for predators.
Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.
Binds to the polyamine modulatory site of the NMDA receptor; potentiates NMDA-induced currents.
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This Item | |||
|---|---|---|---|
| form powder | form powder | form lyophilized powder | form - |
| assay ≥97% (TLC) | assay ≥98% (TLC) | assay ≥97% (HPLC) | assay ≥98.5% (GC) |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| Quality Level 200 | Quality Level 400 | Quality Level 200 | Quality Level 100 |
| solubility H2O: 100 mg/mL | solubility H2O: soluble 100 mg/mL, clear, colorless | solubility cell culture medium: 0.16 mg/mL | solubility - |
| biological source microbial, synthetic | biological source - | biological source synthetic (organic) | biological source - |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves
flash_point_f
113.0 °F - closed cup
flash_point_c
45 °C - closed cup
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