Key Documents

PEAQX tetrasodium hydrate

Name: PEAQX tetrasodium hydrate
Brand: SIGMA
Price: 789.65 PLN

≥98% (HPLC)

Synonym(s):

NVP-AAM077 tetrasodium hydrate, [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate

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Pack Size	SKU	Availability	Price
5 mg		Please contact Customer Service for Availability	PLN 929.00 PLN 789.65
25 mg		Please contact Customer Service for Availability	PLN 3,250.00

About This Item

Empirical Formula (Hill Notation):

C₁₇H₁₃BrN₃Na₄O₅P · xH₂O

CAS Number:

459836-30-7

Molecular Weight:

542.14 (anhydrous basis)

UNSPSC Code:

12352200

PubChem Substance ID:

329820113

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

PLN 789.65

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

water: 10 mg/mL

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].[Na+].[H]O[H].C[C@H](NC(c1cccc2nc([O-])c([O-])nc12)P([O-])([O-])=O)c3ccc(Br)cc3

InChI

1S/C17H17BrN3O5P.4Na.H2O/c1-9(10-5-7-11(18)8-6-10)19-17(27(24,25)26)12-3-2-4-13-14(12)21-16(23)15(22)20-13;;;;;/h2-9,17,19H,1H3,(H,20,22)(H,21,23)(H2,24,25,26);;;;;1H2/q;4*+1;/p-4/t9-,17?;;;;;/m0...../s1

InChI key

SMGAGBKXHAHCGQ-VSYRWHDMSA-J

Description

Application

PEAQX tetrasodium hydrate has been used N-methyl-D-aspartate (NMDA) receptor 2A (NR2A) antagonist in rats[1][2] and mice.[3]

Biochem/physiol Actions

NMDA receptor antagonist.

PEAQX is more specific for N-methyl-D-aspartate (NMDA) receptor 2A (NR2A) than N-methyl-D-aspartate (NMDA) receptor 2B (NR2B) and induces striatal apoptosis. It is less potent in activating caspase-3 than its stereomer NVP-AAM007.[4]

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item	N183	A2979	SML2774
Sigma-Aldrich P1999 PEAQX tetrasodium hydrate	Sigma-Aldrich N183 NBQX disodium salt hydrate	Sigma-Aldrich A2979 A-317491 sodium salt hydrate	Sigma-Aldrich SML2774 KDOAM25 hydrochloride hydrate
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form lyophilized powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. 2-8°C	storage temp. -	storage temp. −20°C
storage condition desiccated	storage condition desiccated	storage condition -	storage condition desiccated
solubility water: 10 mg/mL	solubility H₂O: >10 mg/mL	solubility H₂O: 15 mg/mL, clear	solubility H₂O: 2 mg/mL, clear