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Metyrapone

Name: Metyrapone
Brand: SIGMA
Price: 357 PLN

≥98% (HPLC), glucocorticoid synthesis inhibitor, solid

Synonym(s):

2-Methyl-1,2-di-3-pyridyl-1-propanone, Metyrapone, Su-4885

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Pack Size	SKU	Availability	Price
10 mg		Please contact Customer Service for Availability	PLN 357.00
50 mg		Please contact Customer Service for Availability	PLN 1,290.00

About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₄N₂O

CAS Number:

54-36-4

Molecular Weight:

226.27

NACRES:

NA.77

PubChem Substance ID:

329817949

UNSPSC Code:

51111800

EC Number:

200-206-2

MDL number:

MFCD00006397

Beilstein/REAXYS Number:

163023

Assay:

≥98% (HPLC)

Form:

solid

PLN 357.00

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Properties

Product Name

Metyrapone, ≥98% (HPLC), solid

sterility

non-sterile

Quality Segment

100

assay

≥98% (HPLC)

form

solid

technique(s)

toxicology assay: suitable

mp

52-55 °C (lit.)

solubility

H₂O: <2 mg/mL, DMSO: >20 mg/mL

originator

Novartis

shipped in

ambient

storage temp.

room temp

SMILES string

CC(C)(c1cccnc1)C(=O)c2cccnc2

InChI

1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3

InChI key

FJLBFSROUSIWMA-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Metyrapone is a glucocorticoid synthesis inhibitor; a standard in assessing adrenal gland function especially in response to stress, as well as pituitary gland function. In addition to acting as a glucocorticoid synthesis inhibitor, Metyrapone also inhibits cytochrome P450-mediated prostaglandin ω/ω-1 hydroxylase activity and impairs learning and memory. Data shows results in activation of the sleep EEG and a robust decrease in quantitative delta sleep.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Show Differences

1 of 1

This Item	D9069	T3577	1443001
Sigma-Aldrich M2696 Metyrapone	Sigma-Aldrich D9069 N-Desmethyltamoxifen HCl	Sigma-Aldrich T3577 Tolperisone hydrochloride	USP 1443001 Metyrapone
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay -
form solid	form solid	form solid	form -
technique(s) toxicology assay: suitable	technique(s) inhibition assay: suitable	technique(s) -	technique(s) -
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level -
storage temp. room temp	storage temp. room temp	storage temp. room temp	storage temp. -
solubility H₂O: <2 mg/mL, DMSO: >20 mg/mL	solubility DMSO: ≥20 mg/mL	solubility H₂O: >20 mg/mL	solubility -

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pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Global Trade Item Number

SKU	GTIN
M2696-50MG	04061834045953
M2696-10MG	04061832867403

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