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G9398

Sigma-Aldrich

Asialoganglioside-GM2 from bovine brain

~95%, lyophilized powder

Synonym(s):

GA2 Ganglioside, Gangliotriosyl ceramide

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

Assay

~95%

Quality Level

form

lyophilized powder

storage temp.

−20°C

General description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Biochem/physiol Actions

Degraded form of Asialoganglioside-GM1 ganglioside.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yanfeng Chen et al.
Analytical chemistry, 80(8), 2780-2788 (2008-03-05)
The quality of tissue imaging by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) depends on the effectiveness of the matrix deposition, especially for lipids that may dissolve in the solvent used for the matrix application. This article describes the use of
M Nakamura et al.
Biochemical and biophysical research communications, 217(3), 733-740 (1995-12-26)
Regulation of "a" and "asialo" series ganglioside biosynthesis was analyzed. COS-1 cells expressing only GD1a showed high synthetic activities of GM3, GM2, GM1a, and GD1a, but little activity for GA2 synthesis. However, IL-3-dependent murine NFS60-I7, which has GM1b and GD1
Takao Mukai et al.
International journal of food microbiology, 90(3), 357-362 (2004-01-31)
We examined binding of Bifidobacterium bifidum and Lactobacillus reuteri to the carbohydrate moieties of glycolipids extracted from human enterocyte-like Caco-2 cells in this study. In binding assays to reference glycolipids of different carbohydrate compositions, B. bifidum EB102 bound strongly to
H Usui et al.
Acta medica Okayama, 48(6), 305-309 (1994-12-01)
Immunotoxins composed of monoclonal antibodies (mAbs) and various toxins have been developed for the treatment of malignancies. We investigated the efficacy of three ricin toxin A-chain (RTA)-containing immunotoxins (ITs) conjugated from mAbs which recognize glycolipid asialo-GM2 and glycoprotein H-2d. These
J Busse et al.
The Journal of infectious diseases, 175(1), 77-83 (1997-01-01)
Thirteen clinical strains of Haemophilus influenzae, including types b, d, and untypeable, in vitro specifically recognize phosphatidylethanolamine (PE), gangliotetraosylceramide, gangliotriosylceramide (Gg3), sulfatoxygalactosylceramide, and to a lesser extent sulfatoxygalactosylglycerol. A PE affinity matrix was used to purify an adhesin of approximately

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