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G007

Guvacine hydrochloride

≥97% (NMR), solid

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About This Item

Empirical Formula (Hill Notation):
C6H9NO2 · HCl
CAS Number:
6027-91-4
Molecular Weight:
163.60
UNSPSC Code:
12352200
PubChem Substance ID:
24278163
MDL number:
MFCD00055191
Assay:
≥97% (NMR)
Form:
solid
Quality level:
100
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Quality Level

100

assay

≥97% (NMR)

form

solid

color

white

solubility

H2O: soluble, ethanol: slightly soluble

SMILES string

Cl.OC(=O)C1=CCCNC1

InChI

1S/C6H9NO2.ClH/c8-6(9)5-2-1-3-7-4-5;/h2,7H,1,3-4H2,(H,8,9);1H

InChI key

FGNUNVVTHHKDAM-UHFFFAOYSA-N

Gene Information

human ... FGF9(2254), GABBR1(2550), GABBR2(9568), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Biochem/physiol Actions

GABA uptake inhibitor.

Features and Benefits

This compound is featured on the GABA Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Solutions may be stored for several days at 4 °C.

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
040M4741V
067K47203
067K47202
067K47201
067K4720

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Betel nut constituents as inhibitors of gamma-aminobutyric acid uptake.
G A Johnston et al.
Nature, 258(5536), 627-628 (1975-12-18)
C Rovira et al.
Neuroscience, 12(2), 543-555 (1984-06-01)
In rats under urethane anaesthesia gamma-aminobutyric acid agonists and uptake blockers were microiontophoretically applied in the pyramidal layer of CA1 and in the apical dendrites using a twin set of multibarrelled micropipettes. Thus, the somatic and dendritic field potentials elicited
Ximena Cortes-Bratti et al.
PloS one, 6(2), e16960-e16960 (2011-03-03)
Thioredoxin 80 (Trx80) is an 80 amino acid natural cleavage product of Trx, produced primarily by monocytes. Trx80 induces differentiation of human monocytes into a novel cell type, named Trx80-activated-monocytes (TAMs). In this investigation we present evidence for a role
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Global Trade Item Number

SKUGTIN
504907000104055977263657
G007-250MG04061832090900