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F9384

Sigma-Aldrich

Anti-Mouse IgA (α-chain specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Goat Anti-Mouse IgA (α-chain specific)−Fluorescein isothiocyanate

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

conjugate

FITC conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

direct immunofluorescence: 1:16

storage temp.

2-8°C

target post-translational modification

unmodified

General description

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Anti-Mouse IgA (α-chain specific)−FITC antibody is specific for α chain of mouse IgA. The purified IgA fraction is conjugated to Fluorescein Isothiocyanate (FITC), Isomer I.

Immunogen

Purified mouse IgA

Application

Anti-Mouse IgA (α-chain specific)−FITC antibody may be used for direct immunofluorescent labeling of mouse spleen cells at a minimum working dilution of 1:16. The antibody was used to label platelets from human or mice after incubation with primary antibody against β3 integrin.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Hao-Jing Wen et al.
Molecular medicine reports, 19(1), 660-666 (2018-11-16)
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Robert W Garvey et al.
ChemMedChem, 17(10), e202100759-e202100759 (2022-03-15)
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Heidi Tiller et al.
Transfusion, 52(7), 1446-1457 (2012-01-19)
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a severe bleeding disorder caused by maternal antibody-mediated destruction of fetal or neonatal platelets (PLTs). Results from our recent large screening study suggest that the pathophysiology of FNAIT is more similar to hemolytic
Raphael S Steinberg et al.
International journal of environmental research and public health, 11(9), 8755-8776 (2014-08-28)
Two strains of Lactobacillus, previously isolated from bovine faeces and tested in vitro for properties desired in probiotics, were evaluated for their in vivo effectiveness in protecting against experimental salmonellosis. L. salivarius L38 and L. acidophilus L36 previously demonstrated the
Ermeng Xiong et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(27), 13480-13489 (2019-05-28)
IgA is the most abundantly produced antibody in the body and plays a crucial role in gut homeostasis and mucosal immunity. IgA forms a dimer that covalently associates with the joining (J) chain, which is essential for IgA transport into

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