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F5130

5-Fluorouridine

≥99% (HPLC), synthetic (organic), powder

1 of 1 reviewers received a sample product or took part in a promotion

Synonym(s):

5-Fluorouracil 1β-D-ribofuranoside, FUrd

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Size/SKUAvailabilityPrice
100 mg
Please contact Customer Service for Availability
824,00 PLN
250 mg
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986,00 PLN
838,10 PLN
1 g
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2.970,00 PLN

About This Item

Empirical Formula (Hill Notation):
C9H11FN2O6
CAS Number:
316-46-1
Molecular Weight:
262.19
NACRES:
NA.51
PubChem Substance ID:
24894883
UNSPSC Code:
41106305
EC Number:
206-260-3
MDL number:
MFCD00036832
Beilstein/REAXYS Number:
33662
eCl@ss:
32119108
Assay:
≥99% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

824,00 PLN

Please contact Customer Service for Availability
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Product Name

5-Fluorouridine, proapoptotic anitproliferative plant growth regulator

biological source

synthetic (organic)

Quality Segment

assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O

InChI

1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

InChI key

FHIDNBAQOFJWCA-UAKXSSHOSA-N

General description

5-Fluorouridine (FUrd) is a fluoropyrimidine nucleoside analog and a cell-permeable modified RNA precursor.

Application

5-Fluorouridine has been used for labeling active transcription sites in the porcine fetal fibroblasts and human cell lines for immunocytochemistry analysis. It has also been used to monitor apoptosis during drug sensitivity assay in esophageal squamous cell carcinoma (ESCC) cells.

Biochem/physiol Actions

5-Fluorouridine (FUrd) is cytotoxic towards cancer cells. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.

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This Item
584222584223
5-Fluorouridine proapoptotic anitproliferative plant growth regulator

Sigma-Aldrich

F5130

5-Fluorouridine

Tetrahydrouridine Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O.

Millipore

584222

Tetrahydrouridine

Tetrahydrouridine InSolution, ≥90%, competitive inhibitor of cytidine deaminase

Sigma-Aldrich

584223

Tetrahydrouridine

description

proapoptotic anitproliferative plant growth regulator

description

Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O.

description

InSolution, ≥90%, competitive inhibitor of cytidine deaminase

biological source

synthetic (organic)

biological source

-

biological source

-

Quality Level

100

Quality Level

100

Quality Level

100

assay

≥99% (HPLC)

assay

≥90% (TLC)

assay

≥90% (TLC)

form

powder

form

solid

form

liquid

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 200 mg/mL

solubility

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCN6639
    MKCL7061
    MKCW8681
    MKCG5058
    MKCF4985

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    1 of 1 reviewers received a sample product or took part in a promotion

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      • Review 1
      • Votes 0
      2 out of 5 stars.

      Review of chemical compound

      This product is reasonably priced compared to other suppliers.

      Helpful?

      1. Response from Merck KGaA:

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