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EHU003451

MISSION® esiRNA

targeting human POLR2A

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20 μg
Usually ships in 3 weeks (4 to 6 weeks for custom orders).
PLN 956.00
50 μg
Usually ships in 3 weeks (4 to 6 weeks for custom orders).
PLN 1,720.00

About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

PLN 956.00

Usually ships in 3 weeks (4 to 6 weeks for custom orders).
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAGGCAAGCAAATCTTCTCCCTCATCATACCTGGTCACATCAATTGTATCCGTACCCACAGTACCCATCCCGATGATGAAGACAGTGGCCCTTACAAGCACATCTCTCCTGGGGACACCAAGGTGGTGGTGGAGAATGGGGAGCTGATCATGGGCATCCTGTGTAAGAAGTCTCTGGGCACGTCAGCTGGCTCCCTGGTCCACATCTCCTACCTAGAGATGGGTCATGACATCACTCGCCTCTTCTACTCCAACATTCAGACTGTCATTAACAACTGGCTCCTCATCGAGGGTCATACTATTGGCATTGGGGACTCCATTGCTGATTCTAAGACTTACCAGGACATTCAGAACACTATTAAGAAGGCCAAGCAGGACGTAATAGAGGTCATCGAGAAGGCACACAACAATGAGCTGGAGCCCACCCCAGGGAACACTCTGCGGCAGACGTTTGAGAATCAGGTGAACCGCATTCTTAACGATGCCCGAGACAAGACTGGCTCCTCTGCTCAGAAATCCCTGTCTGAATACAATAACTTCAAGTCTATGGTCGTGTCCGG

Ensembl | human accession no.

ENSG00000181222

NCBI accession no.

NM_000937

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... POLR2A(5430)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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MISSION® esiRNA targeting human POLR2A

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product line

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product line

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product line

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Ensembl | human accession no.

ENSG00000181222

Ensembl | human accession no.

ENSG00000177700

Ensembl | human accession no.

ENSG00000105258

Ensembl | human accession no.

ENSG00000099817

Gene Information

human ... POLR2A(5430)

Gene Information

human ... POLR2L(5441)

Gene Information

human ... POLR2I(5438)

Gene Information

human ... POLR2E(5434)

esiRNA cDNA target sequence

CAGGCAAGCAAATCTTCTCCCTCATCATACCTGGTCACATCAATTGTATCCGTACCCACAGTACCCATCCCGATGATGAAGACAGTGGCCCTTACAAGCACATCTCTCCTGGGGACACCAAGGTGGTGGTGGAGAATGGGGAGCTGATCATGGGCATCCTGTGTAAGAAGTCTCTGGGCACGTCAGCTGGCTCCCTGGTCCACATCTCCTACCTAGAGATGGGTCATGACATCACTCGCCTCTTCTACTCCAACATTCAGACTGTCATTAACAACTGGCTCCTCATCGAGGGTCATACTATTGGCATTGGGGACTCCATTGCTGATTCTAAGACTTACCAGGACATTCAGAACACTATTAAGAAGGCCAAGCAGGACGTAATAGAGGTCATCGAGAAGGCACACAACAATGAGCTGGAGCCCACCCCAGGGAACACTCTGCGGCAGACGTTTGAGAATCAGGTGAACCGCATTCTTAACGATGCCCGAGACAAGACTGGCTCCTCTGCTCAGAAATCCCTGTCTGAATACAATAACTTCAAGTCTATGGTCGTGTCCGG

esiRNA cDNA target sequence

TCACTTGTGGCAAGATCGTCGGCAACAAGTGGGAGGCTTACCTGGGGCTGCTGCAGGCCGAGTACACCGAGGGGGATGCGCTGGATGCCCTGGGCCTGAAGCGCTACTGCTGCCGCCGGATGCTGCTGGCCCACGTGGACCTGATCGAGAAGCTGCTCAATTATGCACCCCTGGAGAAGTGACCACGCTGGAACCCACCCACCCGCTGTGCTGACCATGGGCCCTGAGCGTCCTGCCCCGAATTCACGAGGCTGAGGCATCCGGGAGCTGGCGTAATGCCTGGCCGCAGTGTGTGTGTATCCGATACCCCACTCTGGAAGGAACCATCCAGTAAAGGTCTTTCAGAACCACTAAGGTCCCAGCCCTCACTAGGATGTCAGGAGCCAGGTCTAGGCCCAGCTTTCACACTGTGGCAGCCCAGTGAAGCAGACTGGGCCATGAACTCTCCTAGCCCTGGGGCCAGCCTGTTCCACAGGCACCCCTGCAGGAGGCGCTGCCAGGAGAGCCTTCCATCTCGGGGCTCTTTGAGGTTCCCTCCTTCTGGGTGTTCTTCAGGCT

esiRNA cDNA target sequence

TCTGTCCTGGATGCTCAGTGTTTTGCGGTTTACGATGCGCATCGTTTTCCCGGCTCTGGCACCAGATCCATACTATTCTGTAAACTGAGGCGGCGATGCCCAAAAATTGGAAGCAATTACTCTAAGATATCAAAAGATTGAAGCAAGCCATGAAACCTCTGCGCGGAGAGAGCCGAGCCCGAGGCGGCGGGGAGCCAGCACGTGTGCGCAGCTCCGCCCTCTTTTGGCGAAGCACCTAGGCCTGGCCCCTCCCGCGACCTGTAGCGCGGCGGAGCAAGCGCGGAAGGCTGGGAGGGCTGCGCGGGCTGCGCGTCGCCATGGAGCCCGACGGGACTTACGAGCCGGGCTTCGTGGGTATTCGCTTCTGCCAGGAATGTAACAACATGCTGTACCCCAAGGAAGACAAGGAGAACCGCATTCTGCTCTACGCGTGCCGGAACTGTGATTACCAGCAGGAGGCCGACAACAGCTGCATCTATGTCAACAAGATCACGCACGAAGTGGACGAACTGACCCAGAT

esiRNA cDNA target sequence

AAGACCATCATGCAGCTGTGCCACGACCGTGGCTATCTGGTGACCCAGGACGAGCTTGACCAGACCCTGGAGGAGTTCAAAGCCCAATCTGGGGACAAGCCGAGTGAGGGGCGGCCGCGGCGCACGGACCTCACCGTGCTGGTGGCCCACAACGATGACCCCACCGACCAGATGTTTGTGTTCTTTCCAGAGGAGCCCAAGGTGGGCATCAAGACCATCAAGGTGTACTGCCAGCGCATGCAGGAGGAGAACATCACACGGGCTCTCATCGTGGTGCAGCAGGGCATGACACCCTCCGCCAAGCAGTCCCTGGTCGACATGGCCCCCAAGTACATCCTGGAGCAGTTTCTGCAGCAGGAGCTGCTCATCAACATCACGGAGCACGAGCTAGTCCCTGAGCACGTCGTCATGACCAAGGAGGAGGTGACAGAGC

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Related Content

MISSION esiRNA

Instructions

Jiangsheng Xu et al.
Nature nanotechnology, 14(4), 388-397 (2019-02-26)
TP53 is the most frequently mutated or deleted gene in triple negative breast cancer (TNBC). Both the loss of TP53 and the lack of targeted therapy are significantly correlated with poor clinical outcomes, making TNBC the only type of breast
Kelly Brooks et al.
Pigment cell & melanoma research, 27(5), 813-821 (2014-06-04)
Melanoma cell lines are commonly defective for the G2-phase cell cycle checkpoint that responds to incomplete catenation of the replicated chromosomes. Here, we demonstrate that melanomas defective for this checkpoint response are less sensitive to genotoxic stress, suggesting that the

Global Trade Item Number

SKUGTIN
EHU003451-20UG04061831360363
EHU003451-50UG04061831370379

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