D2697

Dihydralazine sulfate

Name: Dihydralazine sulfate
Brand: SIGMA
Price: 2220 PLN

Slide 1 of 1

Select a Size

D2697-100MG

PLN 2,220.00

Please contact Customer Service for Availability

Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):

C₈H₁₂N₆O₄S

CAS Number:

7327-87-9

Molecular Weight:

288.28

MDL number:

MFCD00035271

UNSPSC Code:

51102829

PubChem Substance ID:

329798750

EC Number:

230-808-0

NACRES:

NA.85

Key Documents

View All Documentation

form

powder

Quality Level

200

solubility

DMSO: 1 mg/mL

mode of action

cell membrane | interferes

storage temp.

−20°C

SMILES string

OS(O)(=O)=O.NNC1=NNC(=N/N)\c2ccccc12

InChI

1S/C8H10N6.H2O4S/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7;1-5(2,3)4/h1-4H,9-10H2,(H,11,13)(H,12,14);(H2,1,2,3,4)

InChI key

BWHAMWGGORIDBK-UHFFFAOYSA-N

Related Categories

Antibiotics

Biochemicals

Cell Culture Supplements & Reagents

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	D4321	SML3188	S5640
Sigma-Aldrich D2697 Dihydralazine sulfate	Sigma-Aldrich D4321 Dihydroeponemycin	Sigma-Aldrich SML3188 Isavuconazonium sulfate	Sigma-Aldrich S5640 Sodium sulfate
mode of action cell membrane \| interferes	mode of action -	mode of action -	mode of action -
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 200
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. -
solubility DMSO: 1 mg/mL	solubility DMSO: ≥1 mg/mL	solubility DMSO: 2 mg/mL, clear	solubility water: soluble 1 g/10 mL

Biochem/physiol Actions

Dihydralazine sulfate is a vasodilator and an antihypertensive agent. It relaxes arterial smooth muscle by inhibiting the accumulation of intracellular free calcium. By relaxing vascular smooth muscle, vasodilators act to decrease peripheral resistance.[1][2]

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

033M4085V

14130303

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Cerebral blood flow during dihydralazine-induced hypotension in hypertensive rats.

D I Barry et al.

Stroke, 15(1), 102-108 (1984-01-01)

The cerebrovascular effects of graded, controlled dihydralazine-induced hypotension were studied in rats with renal hypertension (RHR) and spontaneous hypertension (SHR). Repeated measurements of cerebral blood flow (CBF) were made using the intraarterial 133Xenon injection technique in anaesthetised normocapnic animals. Dihydralazine

Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.

Helen J Knowles et al.

Circulation research, 95(2), 162-169 (2004-06-12)

The vasodilator hydralazine, used clinically in cardiovascular therapy, relaxes arterial smooth muscle by inhibiting accumulation of intracellular free Ca2+ via an unidentified primary target. Collagen prolyl hydroxylase is a known target of hydralazine. We therefore investigated whether inhibition of other

Kinetics and Characterization of Degradation Products of Dihydralazine and Hydrochlorothiazide in Binary Mixture by HPLC-UV, LC-DAD and LC-MS Methods.

Anna Gumieniczek et al.

Chromatographia, 81(8), 1147-1162 (2018-09-18)

Dihydralazine and hydrochlorothiazide were stored at high temperature and humidity, under UV/Vis light and different pH, as individual drugs and the mixture. Then, a sensitive and selective HPLC-UV method was developed for simultaneous determination of dihydralazine and hydrochlorothiazide in presence

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service