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D033

Sigma-Aldrich

(+)-Butaclamol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C25H31NO · HCl
CAS Number:
55528-07-9
Molecular Weight:
397.98
MDL number:
MFCD00082307
UNSPSC Code:
12352200
PubChem Substance ID:
24278400
NACRES:
NA.77

form

powder

Quality Level

100

optical activity

[α]27/D +222° in methanol(lit.)

storage condition

desiccated

color

white

solubility

DMSO: >10 mg/mL, clear

SMILES string

Cl[H].[H][C@@]12C[C@@](O)(CCN1C[C@@]3([H])c4ccccc4CCc5cccc2c35)C(C)(C)C

InChI

1S/C25H31NO.ClH/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25;/h4-10,21-22,27H,11-16H2,1-3H3;1H/t21-,22-,25-;/m0./s1

InChI key

QZRUMKUMFJJARD-AAJWHBHYSA-N

Gene Information

human ... DRD1(1812) , DRD2(1813) , DRD3(1814) , DRD4(1815) , DRD5(1816)

Application

(+)-Butaclamol hydrochloride has been used as a dopamine receptor blocker in:
  • dissected brain sections
  • striatum of Parkinson′s disease specimens
  • human embryonic kidney cells (HEK293 cells)
  • mice striatal tissue

Biochem/physiol Actions

(+)-Butaclamol is a dopamine receptor antagonist and is an active enantiomer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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