This product is not a reference material or analytical standard. Please see the links below to review Butorphanol Tartrate standards that are currently available:
https://www.sigmaaldrich.com/product/cerillian/b037
https://www.sigmaaldrich.com/product/usp/1082504
B9156
Butorphanol (+)-tartrate salt
≥99%
Synonym(s):
L-N-Cyclobutylmethyl-3,14-dihydroxymorphinan (+)-tartrate salt
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About This Item
Empirical Formula (Hill Notation):
C21H29NO2 · C4H6O6
CAS Number:
Molecular Weight:
477.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
261-443-5
MDL number:
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Quality Level
assay
≥99%
form
powder
drug control
USDEA Schedule IV; psychotrope (France); regulated under CDSA - not available from Sigma-Aldrich Canada
originator
Bristol-Myers Squibb
storage temp.
2-8°C
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.Oc1ccc2C[C@H]3N(CC[C@@]4(CCCC[C@@]34O)c2c1)CC5CCC5
InChI
1S/C21H29NO2.C4H6O6/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15;5-1(3(7)8)2(6)4(9)10/h6-7,13,15,19,23-24H,1-5,8-12,14H2;1-2,5-6H,(H,7,8)(H,9,10)/t19-,20+,21-;1-,2-/m11/s1
InChI key
GMTYREVWZXJPLF-BTVKVFNOSA-N
Gene Information
human ... OPRK1(4986), OPRM1(4988)
Biochem/physiol Actions
κ/μ opioid receptor agonist.
Features and Benefits
This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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J A Vivian et al.
The Journal of pharmacology and experimental therapeutics, 290(1), 259-265 (1999-06-25)
Butorphanol and nalbuphine have substantial affinity for mu and kappa-opioid receptor sites, yet their behavioral effects in monkeys are largely consistent with a mu receptor mechanism of action. Using ethylketocyclazocine (EKC) discrimination and diuresis assays in rhesus monkeys (Macaca mulatta)
J C Chen et al.
Life sciences, 52(4), 389-396 (1993-01-01)
The ability of morphine, fentanyl, butorphanol, nalbuphine, and dezocine to compete with radiolabeled ligands for binding at the mu1, mu2, kappa1, and delta opioid receptors and the sigma receptor was characterized. In the absence of sodium, the potency of opioid
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B9156-100MG | 04061832555539 |
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Can this material (Cod: B9156 Butorphanol) be used as a reference standard or analytical standard?
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