Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD50 in rats 750 mg/kg; in dogs 340 mg/kg.
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Environmental toxicology and pharmacology, 34(2), 223-227 (2012-05-05)
The aim of this research has been to determine the biperiden hydrochloride permeability in Caco-2 model, in order to classify it based on the Biopharmaceutics Classification System (BCS). The World Health Organization (WHO) as well as many other authors have
Il Giornale di chirurgia, 32(8-9), 368-371 (2011-10-25)
Stercoral perforation of the colon due to fecaloma is a rare disease and less than 100 cases have been described in the literature. The disease mainly involves the rectosigmoid colon. The condition is correlated with longstanding decubitus, chronic constipation, abuse
Use of anticholinergic drugs and worsening of pemphigus foliaceus in a patient with bipolar disorder.
Lúcio Botelho-Nogueira et al.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 33(4), 412-413 (2011-12-23)
[Current classifications of dystonies, treatment strategy].
Z A Zalialova
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 113(3), 85-89 (2013-04-25)
Archives of Iranian medicine, 14(2), 152-154 (2011-03-03)
The syndrome of hemiparkinsonism-hemiatrophy is an uncommon form of secondary Parkinsonism that presents with unilateral body Parkinsonism plus variable atrophy on the same side. Diagnosis of this syndrome needs a complete past medical history taking, as well as assessment of
Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.
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