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B016

Benoxathian hydrochloride

solid

Synonym(s):

2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride

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Pack SizeSKUAvailabilityPrice
10 mg
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PLN 341.00

About This Item

Empirical Formula (Hill Notation):
C19H23NO4S · HCl
CAS Number:
Molecular Weight:
397.92
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Form:
solid
Quality level:

PLN 341.00


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form

solid

Quality Level

color

white

solubility

H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.), ethanol: soluble, isopropanol: soluble

SMILES string

Cl.COc1cccc(OC)c1OCCNCC2CSc3ccccc3O2

InChI

1S/C19H23NO4S.ClH/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14;/h3-9,14,20H,10-13H2,1-2H3;1H

InChI key

OWRADFDDJVNMGL-UHFFFAOYSA-N

Gene Information

Biochem/physiol Actions

Selective α1-adrenoceptor antagonist.

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This Item
A0779UC168L1011
form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

solubility

H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.), isopropanol: soluble, ethanol: soluble

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL (Solutions may be stored for several days at 4 °C), boiling water: 100 mg/mL (Solutions may be stored for several days at 4 °C), 0.1 M HCl: soluble (Solutions may be stored for several days at 4 °C), methanol: soluble (Solutions may be stored for several days at 4 °C)

solubility

H2O: soluble, methanol: soluble

solubility

-

color

white

color

white

color

white to off-white

color

white

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

Gene Information

-

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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M A Noguera et al.
British journal of pharmacology, 119(1), 158-164 (1996-09-01)
1. In the present study, depletion of internal Ca2+ stores sensitive to noradrenaline (1 microM) in rat aorta, is the signal for the entry of extracellular Ca2+, not only to refill the stores but also, in our experimental conditions, to
Jessica A Cardin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(35), 7745-7753 (2004-09-03)
Norepinephrine (NE) plays a complex role in the behavioral state-dependent regulation of sensory processing. However, the role of forebrain NE action in modulating high-order sensory activity has not been directly addressed. In this study, we take advantage of the discrete
C H Brown et al.
The Journal of physiology, 507 ( Pt 3), 831-842 (1998-05-23)
1. We have tested the hypothesis that morphine withdrawal excitation of oxytocin neurones that follows from administration of naloxone to morphine-dependent rats is a consequence of excitation of noradrenergic neurones. 2. Female rats were made morphine dependent by intracerebroventricular (i.c.v.)



Global Trade Item Number

SKUGTIN
B016-10MG04061832088785
B016-25MG04061832088792

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