Skip to Content
Merck

Key Documents

View All Documentation

Skip To

AC-0341A

HSP70 (EP377) Rabbit Monoclonal Primary Antibody

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
0.1 mL
Please contact Customer Service for Availability
PLN 1,440.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
monoclonal
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
Application:
IHC (p)
Citations:
-

PLN 1,440.00

Please contact Customer Service for Availability
​
Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

antibody form

Ig fraction of antiserum

clone

monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

General description

The heat shock proteins (HSPs) are a conserved family of ubiquitously expressed proteins that functions to protect cells from various environmental damage. Two proteins within the family, HSP70 and HSP27 demonstrate strong anti-apoptotic activity; its overexpression allow cells to survive in variable conditions. HSPs have been implicated in tumorigenesis – affecting cell cycle regulation, multidrug resistance and modulating p53 function. HSP70 has been studied in a variety of malignancies, including breast, lung, oral, prostate and uterine-cervical cancers. A majority of results associated HSP70 overexpression with poor prognosis and resistance to therapy. Recently, HSP70 diagnostic utility was established in identifying hepatocellular carcinoma (HCC). HSP70 was the most abundantly up-regulated gene in advanced HCC and its immunoreactivity was seen in the majority of HCC. Its sensitivity and specificity were determined as 74% and 98%, respectively. Furthermore, a three antibody panel with HSP70, Glypican 3, and Glutamine Synthetase is capable of distinguishing HCC from high grade dysplastic nodules with 100% specificity when 2 markers are positive.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1%BSA and &< 0.1% Sodium Azide

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For a copy of the IFU and CofA contact [email protected]

For Technical Service please contact: 800-665-7284 or email: [email protected]

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
AC-0341SAB4200714SAB4200797
Sigma-Aldrich

Sigma-Aldrich

AC-0341A

HSP70 (EP377) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

Sigma-Aldrich

AC-0341

HSP70 (EP377) Rabbit Monoclonal Primary Antibody

Anti-Heat Shock Protein 70 (HSP70) antibody, Mouse monoclonal clone BRM-22, purified from hybridoma cell culture

Sigma-Aldrich

SAB4200714

Anti-Heat Shock Protein 70 (HSP70) antibody, Mouse monoclonal

Anti-HSP70 antibody produced in rabbit IgG fraction of antiserum

Sigma-Aldrich

SAB4200797

Anti-HSP70 antibody produced in rabbit

antibody form

Ig fraction of antiserum

antibody form

Ig fraction of antiserum

antibody form

purified from hybridoma cell culture

antibody form

IgG fraction of antiserum

biological source

rabbit

biological source

rabbit

biological source

-

biological source

rabbit

clone

monoclonal

clone

monoclonal

clone

BRM-22, monoclonal

clone

polyclonal

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200

technique(s)

ELISA: suitable, dot blot: suitable, immunoblotting: 0.25-0.5 μg/mL using HeLa cell line extract, immunofluorescence: suitable, immunohistochemistry: suitable

technique(s)

immunoblotting: 1:250-1:500 using different cell extracts, immunoprecipitation (IP): 10-20 μg/test

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

Still not finding the right product?

Explore all of our products under HSP70 (EP377) Rabbit Monoclonal Primary Antibody

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
AC-0341A04061838509048

Questions

Reviews

No rating value

Active Filters