The concentration is 50 mg/mL in water.
A8036
N-Acetylheparin sodium salt
~90%
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About This Item
Application
N-Acetylheparin, derivitized porcine mucosal heparin without anticoagulant properties, may be used to protect cardiac, vascular and neural tissues by inhibiting complement activation and neutrophil infiltration of the damage site.
Preparation Note
Prepared from porcine mucosal heparin by a modification of the method of Nagasawa, K. and Inoue, Y., Methods Carb. Chem., 8, 291 (1980).
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This Item | |||
|---|---|---|---|
| assay ~90% | assay 90% | assay 90-95% | assay ~90% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| form solid | form solid | form solid | form solid |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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J L Park et al.
Pharmacology, 58(3), 120-131 (1999-02-02)
The ability of the heparin derivative, N-acetylheparin (NHEP) to protect the heart from regional ischemia/reperfusion injury was examined in vivo. NHEP (2 mg/kg i.v.) or vehicle was administered 2 h before occlusion of the left circumflex coronary (LCX) artery. Open-chest
P C Kouretas et al.
Circulation, 99(8), 1062-1068 (1999-03-02)
Coronary endothelial dysfunction after brief ischemia-reperfusion (IR) remains a clinical problem. We investigated the role of heparin and N-acetylheparin, a nonanticoagulant heparin derivative, in modulating coronary endothelial function after IR injury, with an emphasis on defining the role of the
P C Kouretas et al.
Journal of molecular and cellular cardiology, 30(12), 2669-2682 (1999-02-17)
Heparin, which is widely used clinically, has recently been shown to have specific properties affecting the vascular endothelium. We hypothesized that heparin stimulates endothelial nitric oxide synthase (eNOS) activity by a mechanism independent of its anticoagulant properties and dependent on
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A8036-25MG | 04061833046876 |
| A8036-10MG | 04061833046869 |
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