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A7400

D-2-Aminoadipic acid

Synonym(s):

(R)-2-Aminohexanedioic acid, D-Homoglutamic acid

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1 g
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PLN 2,520.00

About This Item

Linear Formula:
HO2C(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
161.16
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1724347
Form:
powder

PLN 2,520.00


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form

powder

Quality Segment

mp

208-210 °C (lit.)

SMILES string

N[C@H](CCCC(O)=O)C(O)=O

InChI

1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m1/s1

InChI key

OYIFNHCXNCRBQI-SCSAIBSYSA-N

Gene Information

Application

D-2-Aminoadipic acid has been used as an inhibitor of glutamine synthetase in spontaneously immortalized human cell line MIO-M1.[1]

Biochem/physiol Actions

D-2-Aminoadipic acid is a glutamate analog.[2] It acts as an inhibitor of glutamate synthetase.[1] D-2-Aminoadipic acid exhibits gliotoxicity towards mitotic astrocytes.[2]

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powder

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Quality Level

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Gene Information

rat ... Grin2a(24409), Grm1(24414), Grm2(24415), Grm6(24419)

Gene Information

human ... GLUL(2752), LGSN(51557)
rat ... Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Grm6(24419)

Gene Information

rat ... Slc1a3(29483)

Gene Information

-

mp

208-210 °C (lit.)

mp

203-205 °C (dec.) (lit.)

mp

>300 °C (lit.)

mp

>295 °C (subl.) (lit.)


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
A7400-1G04061826688434

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