A6981

Acamprosate calcium

≥98% (HPLC), powder

• Synonym(s): 3-(Acetylamino)-1-propanesulfonic acid calcium salt (2:1)
• Empirical Formula (Hill Notation): C₅H₁₀Ca_0.5NO₄S
• CAS Number: 77337-73-6
• Molecular Weight: 200.24
• MDL number: MFCD00886588
• UNSPSC Code: 12352200
• PubChem Substance ID: 329770909
• EC Number: 278-665-3
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• assay: ≥98% (HPLC)
• form: powder
• solubility: H₂O: >5 mg/mL
• storage temp.: room temp
• SMILES string: CC(=O)NCCCS(=O)(=O)O[Ca]OS(=O)(=O)CCCNC(C)=O
• InChI: 1S/2C5H11NO4S.Ca/c2*1-5(7)6-3-2-4-11(8,9)10;/h2*2-4H2,1H3,(H,6,7)(H,8,9,10);/q;;+2/p-2
• InChI key: BUVGWDNTAWHSKI-UHFFFAOYSA-L
• Gene Information: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444)

Description

Biochem/physiol Actions

Acamprosate calcium is a GABA γ-aminobutyric acid agonist.

Acamprosate calcium is a synthetic analog of γ-aminobutyric acid (GABA) and a GABAB receptor agonist.[1] Acamprosate calcium has been used in alcohol dependence treatments[2] and may be an effective augmentation therapy anxiety patients.[3]

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves