Key Documents

View All Documentation

Amyloid β Protein Fragment 1-38

Name: Amyloid β Protein Fragment 1-38
Brand: SIGMA

≥95% (HPLC), powder

Select a Size

Change View

Pack Size	SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₁₈₄H₂₇₇N₅₁O₅₆S

CAS Number:

131438-74-9

Molecular Weight:

4131.54

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD00166810

Assay:

≥95% (HPLC)

Form:

powder

Quality level:

200

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Quality Level

200

assay

≥95% (HPLC)

form

powder

color

white

solubility

H₂O: 1 mg/mL

UniProt accession no.

P05067

storage temp.

−20°C

Gene Information

human ... APP(351)

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	A4848	A1472	A7973
Sigma-Aldrich A0189 Amyloid β Protein Fragment 1-38	Sigma-Aldrich A4848 Amyloid β-Protein Fragment 17-40	Sigma-Aldrich A1472 MCA-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676-DNP-Lys-Arg-Arg-NH₂	Sigma-Aldrich A7973 [Arg¹³] Amyloid-β-Protein Fragment 1-40
form powder	form lyophilized powder	form powder	form lyophilized powder
assay ≥95% (HPLC)	assay ≥87% (HPLC)	assay ≥90% (HPLC)	assay ≥80% (HPLC)
Quality Level 200	Quality Level -	Quality Level 100	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility H₂O: 1 mg/mL	solubility H₂O: soluble	solubility -	solubility H₂O: soluble
color white	color -	color -	color -

Biochem/physiol Actions

β-Amyloid peptide that forms cross-β-sheet fibrils of 70-90 Å diameter with similar antigenicity as those found in Alzheimer′s disease.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity.

M P Mattson et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 12(2), 376-389 (1992-02-01)

In Alzheimer's disease (AD), abnormal accumulations of beta-amyloid are present in the brain and degenerating neurons exhibit cytoskeletal aberrations (neurofibrillary tangles). Roles for beta-amyloid in the neuronal degeneration of AD have been suggested based on recent data obtained in rodent

Morphology and antibody recognition of synthetic beta-amyloid peptides.

P E Fraser et al.

Journal of neuroscience research, 28(4), 474-485 (1991-04-01)

To elucidate the relationship between amyloid fibril formation in Alzheimer disease (AD) and the primary structure of the beta-amyloid protein (beta-AP), we investigated the ability of peptides sharing sequences with beta-AP to form fibrils in vitro and to recognize anti-beta-amyloid

beta-Amyloid induction of gelatinase B secretion in cultured microglia: inhibition by dexamethasone and indomethacin.

P E Gottschall

Neuroreport, 7(18), 3077-3080 (1996-11-25)

Since administration of anti-inflammatory drugs has been reported to possibly slow the progression of Alzheimer's disease, an effort was made to define effector functions induced by beta-amyloid (A beta) which may be inhibited by these drugs. Rat microglia in culture

Global Trade Item Number

SKU	GTIN
A0189-.1MG	04061833415177
A0189-.5MG	04061832268880

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service